Khoo, Saye
University of Liverpool, UK
Saye Khoo is Professor of Pharmacology and Therapeutics at the University of Liverpool, and Honorary Consultant Physician in Infectious Disease at Liverpool University Hospitals NHS Foundation Trust. He leads a research programme in antiviral therapy, and is Chief Investigator for the international DolPHIN consortium and for AGILE. Research interests include optimisation of antivirals to treat or prevent HIV, including in special populations such as pregnant women and newborn infants. This work is underpinned by highly sensitive drug measurement in his GCP-accredited laboratory, and mathematical modelling to predict drug exposure within body compartments and between people. The study of drug-drug interactions has led to development of the Liverpool Drug Interactions Prescribing Resource for HIV, hepatitis, cancer and in 2020 for experimental COVID-19 therapies. These are widely accessed and used by treatment guidelines throughout the world (including WHO), returning 18M searches in the past 3 years. Khoo has served in expert advisory groups and guidelines committees for the British HIV Association, WHO, British Infection Society, UK Home Office, British Transplant Society, European Society for Organ Transplantation and the International AIDS Society.